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Grand Rounds 11/11/15 @ BID-Needham: Dr. David A. Ryley, MD  

Oocyte Cryopreservation: Medical and Social Indications
Last Updated: Aug 5, 2016 URL: http://bidmc.libguides.com/Ryley/2015 Print Guide RSS Updates

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Speaker: Date: Topic

David A. Ryley, MD

Nov 11, 2015

Oocyte Cryopreservation: Medical and Social Indications

      

    Objectives of the Presentation

    Participants should be able to:

    • Discuss the concept of the ovarian reserve, and its decline with age.
    • Recognize the medical indications for oocyte cryopreservation, i.e., prior to the receiving of gonadotoxic medical treatments.
    • Appraise the value, risks, and benefits of oocyte cryopreservation for social indications.
        

      Responsibility for Content

      The PowerPoint presentation, Take-Away points, Objectives, and Article links were sent by Medical Library Services and the CME Committee.

      Diane E. Young, Information Specialist

      dyoung3@bidmc.harvard.edu

          

        Take-Away Points of the Presentation

        1. Vitrification has replaced slow-freeze as the standard of care for oocyte cryopreservation.

        2. Delivery rate using cryopreserved oocytes is comparable to conventional IVF using fresh oocytes.

        3. Oocyte cryopreservation babies are born with no apparent increase in congenital anomalies.

        4. Female fertility may be impaired following chemotherapy treatment for cancer. Patients facing gonadotoxic treatments can have oocyte cryopreservation (requires a stimulated cycle).

        5. Letrozole can be used for ovulation induction. The 5 mg dose is more effective than the 2.5 mg dose.

        6. Controlled ovarian hyperstimulation (COH) requiring exogenous FSH administration can be undertaken prior to chemotherapy..

        7. The American Society for Reproductive Medicine (ASRM) does not recommend elective oocyte cryopreservation.

            
           

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