Speaker: Date: Topic
Louis Caplan, MD
Nov. 27, 2013
Stroke Update - 2013
Responsibility for Content
The powerpoint presentation, take-away points, and article links were sent by the Medical Library and the CME Committee.
Diane E. Young, Information Specialist
Take-Away Points of the Presentation
1. Aggessive medical management may be as good or better than interventional and surgical procedures in stroke prevention of some atherosclerotic lesions.
2. Occult atrial fibrillation, aortic atheromas, PFOs, and non-stenosing large artery lesions are common causes of brain ischemia in patients with cryptogenic TIAs and strokes.
3. Anticoagulants are used to prevent the development of red erythrocyte-fibrin thromboemboli while antiplatelet agents are prescribed in situations in which white platelet-fibrin thrombi develop.
4. Management of patients with acute brain ischemia involves: 1.) finding out what is wrong with the patient, and 2.) considering what therapies are potentially applicable, and 3.) weighing the risks and benefits of each.
Links to Articles Cited in the Presentation
- Boden WE et al: Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Me
- Calabrese LH et al: Narrative review: reversible cerebral vasoconstriction syndromes. Ann Intern Med
- Chatzikonstantinou A et al: CT angiography of the aorta is superior to transesophageal echocardiogra
- Daccarett M et al: MRI of the left atrium: predicting clinical outcomes in patients with atrial fibr
- Furlan AJ et al: Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N Engl
- Hur J et al: Left atrial appendage thrombi in stroke patients: detection with two-phase cardiac CT a
- Meier B et al: Percutaneous closure of patent foramen ovale in cryptogenic embolism. N Engl J Med 20
- Ntaios G et al: CHADS2, CHA2 S2 DS2 -VASc, and long-term stroke outcome in patients without atrial f
- Spence JD et al: Effects of intensive medical therapy on microemboli and cardiovascular risk in asym